Volume 41 Issue 5
Sep.  2020
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Li Zeng, Wei Li, Ce-Shi Chen. Breast cancer animal models and applications. Zoological Research, 2020, 41(5): 477-494. doi: 10.24272/j.issn.2095-8137.2020.095
Citation: Li Zeng, Wei Li, Ce-Shi Chen. Breast cancer animal models and applications. Zoological Research, 2020, 41(5): 477-494. doi: 10.24272/j.issn.2095-8137.2020.095

Breast cancer animal models and applications

doi: 10.24272/j.issn.2095-8137.2020.095
Funds:  This study was supported in part by grants from the National Key R&D Program of China (2018YFC2000400), National Natural Science Foundation of China (81830087, U1602221, 31771516), and Project of Innovative Research Team of Yunnan Province (2019HC005)
More Information
  • Corresponding author: E-mail: chenc@mail.kiz.ac.cn
  • Received Date: 2020-04-22
  • Accepted Date: 2020-06-19
  • Published Online: 2020-06-27
  • Publish Date: 2020-09-18
  • Breast cancer is the most common malignancy in women. Basic and translational breast cancer research relies heavily on experimental animal models. Ideally, such models for breast cancer should have commonality with human breast cancer in terms of tumor etiology, biological behavior, pathology, and response to therapeutics. This review introduces current progress in different breast cancer experimental animal models and analyzes their characteristics, advantages, disadvantages, and potential applications. Finally, we propose future research directions for breast cancer animal models.
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