Study on The Killing Action of The Antibacterial Peptides on Cancer Cells and Their Influence on the Ultrastructure

The β-component of antibacterial peptide purified from the haemolymph of silkworm Bombyx mori.pupae induced by E.coli.can kill the cancer cells cultured in vitro selectively,but has no effect on the B-leukocytes of normal human.The ultrastructure of the U937 cells treated with the antibacterial peptides was observed with an the electron microscope.It was found that the cancer cells plasma membrane and nuclear envelope were broken,mitochondrion was swollen and intracellular substances were leaked out,and the cells died soon.