The Effect of Egf on The Regeneration of Artificially Wounded Cornea Epiderm in Rhesus Monkeys

The effects of epidermal growth factor (EGF) on the regeneration of artificially wounded cornea epiderm were tested in 5 monkeys (Macaca mulatta,aged 2-3 years).The wounded right eyes of the experimental monkeys were treated with EGF(130 μg/ml) extracted from the submaxillary gland of male mouse,one drop per each eye,4 times one day,while the wounded left eyes of the same monkeys were treated with axenic solution of 0.9% NaCl (control).The results showed that the wounded cornea of the right eyes were recovered in 3-4 days while that of the left eyes were recovered in 5-6 days.The recovery of the right eyes were faster than that of the left eyes.It suggested that the EGF from mouse submaxillary gland can be used for healing wounded cornea.