The Age Characteristics of the Long-Term Synaptic Potentiation in the CA3 Region of Hippocampus of the Young and The Aged Rats During The Learning

The learning-dependent long-term potentiation (LTP) in the hippocampal CA3 region of the young and aged rats all was changed obviously during the establishment,extinction and re-establishment of conditioned drink response.The velocity of establishment and development of the learning-dependent LTP in CA3 of the young rats is more than that of the aged rats.However there was nonsignificant differnece in the extinction of the learning-dependent LTP in CA3 of the young and the aged rats.These results not only showed that there was the age characteristics of the learning-dependent LTP in the CA3 region but also provided a evidence that the learning-dependent LTP might be one of the neural bases of learning and memory.