The Relationship Between the Dosage of In vitro Irradiation & the Change of Lymphocyte acp Activity of dog & Monkey Blood

In the absence of a routine culture medium,the morphology and ACP activity of dog and monkey blood lymphocytes were proved to be normal cytochemically within 24 hour incubation.After in vitro irradiation the blood lymphocyte ACP activity of dog and monkey was determined.The doses used in calibration were 200,300,400 and 600 rads respectively.A regression equation was obtained from the correlation between the lymphocyte ACP "4" type and their radiation dosage.In addition,the applicability of ACP activity determination after in vitro irradiation to the biological dosimetry,to the evaluation of the efficacy of certain radioprotectors and the mechansim of ACP activity changes after in vitro irradiation were preliminarily discussed.