Turn off MathJax
Article Contents
Bin Hu, Jiamin Wang, Qingxun Zhang, Jing Xu, Yanan Xing, Bo Wang, Shuyi Han, Hongxuan He. Enterococcus faecalis provides protection during scavenging by carrion crow (Corvus corone). Zoological Research. doi: 10.24272/j.issn.2095-8137.2023.320
Citation: Bin Hu, Jiamin Wang, Qingxun Zhang, Jing Xu, Yanan Xing, Bo Wang, Shuyi Han, Hongxuan He. Enterococcus faecalis provides protection during scavenging by carrion crow (Corvus corone). Zoological Research. doi: 10.24272/j.issn.2095-8137.2023.320

Enterococcus faecalis provides protection during scavenging by carrion crow (Corvus corone)

doi: 10.24272/j.issn.2095-8137.2023.320
Funds:  This study was supported by Beijing Wildlife Rescue Center, China, the National Key Research and Development Program of China (No. 2022YFC2601602), the Major Program of National Natural Science Foundation of China (No. 32090023), and National Forestry and Grassland Administration, China.
  • Received Date: 2023-10-08
  • Accepted Date: 2023-12-29
  • Rev Recd Date: 2023-12-27
  • Published Online: 2023-12-30
  • The gut microbiota plays a crucial role in interacting with the host's physiological system and providing essential ecosystem services. It is known that diet can affect the composition of the gut microbiota, while the gut microbiota can also help the host adapt to specific dietary habits. As a facultative scavenger urban bird, the carrion crow (Corvus corone) is one of the hosts of high-abundance pathogen due to its facultative scavenging behavior. However, carrion crows rarely get sick, which is related to their unique physiological adaptation ability. The role of the gut microbiota in this process remains incompletely understood. In this study, we performed a comparative analysis using 16S rRNA amplicon sequencing technology, analyzing the colonic contents of carrion crows and 16 other bird species with different diets in Beijing, China. Our findings revealed that the predominant gut microbiota of the carrion crow primarily comprises Proteobacteria (75.51%) and Firmicutes (22.37%). We observed significant differences in the relative abundance of Enterococcus faecalis between groups, suggesting that Enterococcus faecalis may serve as a biomarker for carrion crows' facultative scavenging behavior. Subsequently, we isolated Enterococcus faecalis derived from carrion crows and conducted transplantation experiments in model mice to confirm the protective effects of this bacterial community against Salmonella infection. The results demonstrated that Enterococcus faecalis can downregulated the expression of pro-inflammatory cytokines TNF-α, IFN-γ, and IL-6, prevented the colonization of Salmonella, and regulated the composition of gut microbiota in mice, thereby modulating the host's immune regulatory capacity. Finally, we demonstrated that the Enterococcus faecalis plays an immunoregulatory and anti-pathogen role in carrion crows during scavenging behavior, providing a typical case of how the gut microbiota can protect diet-specialized hosts.
  • loading
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (114) PDF downloads(11) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return