自然光光照时长对猕猴毛发可的松水平的影响<em></em>

Xiao-Li Feng; He-Long Che; Xi Ning; Xue-Ying Ba; Juan-Li; Jing-Fang Zhang; Yun Wang; Zheng-Fei Hu; Xin-Tian Hu; Xiao-Feng Ren

doi:10.24272/j.issn.2095-8137.2019.064

自然光光照时长对猕猴毛发可的松水平的影响

doi: 10.24272/j.issn.2095-8137.2019.064

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车河龙³,
宁熙¹,
巴雪颖¹,
李娟¹,
张静芳¹,
王芸⁴,
胡正飞⁴,
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1.
昆明医科大学基础医学院，云南昆明650500，中国
2.
中国科学院昆明动物研究所中国科学院动物模型与人类疾病机理重点实验室，云南昆明650223，中国
3.
中国人民解放军联勤保障部队第908医院普通外科，江西鹰潭335000，中国
4.
中国科学院昆明动物研究所中国科学院昆明灵长类中心，云南昆明650223，中国
5.
中国科学院大学昆明生命科学学院，云南昆明650204，中国

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出版历程
- 收稿日期: 2019-05-09
- 刊出日期: 2019-10-14

Direct sunlight exposure reduces hair cortisol levels in rhesus monkeys (Macaca mulatta)

1.
School of Basic Medical Sciences, Kunming Medical University, Kunming Yunnan 650500, China
2.
Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province，Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming Yunnan 650223, China
3.
Department of General Surgery, 908th Hospital of Chinese PLA Joint Logistic Support Force, Yingtan Jiangxi 335000, China
4.
Kunming Primate Research Center of the Chinese Academy of Sciences, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming Yunnan 650223, China
5.
Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming Yunnan 650204, China

Funds: the National Natural Science Foundation of China (31700910) and Applied Basic Research Programs of Science and Technology Commission Foundation of Yunnan Province(2017FB109)

More Information

Corresponding author: Xin-Tian Hu,Xiao-Feng Ren

摘要

摘要: 光照疗法能够改善季节性情感障碍(SAD)患者的症状。有研究者认为，光照可能通过改变可的松分泌的昼夜节律，从而改善SAD患者的症状。然而，另外的研究者发现，光照对可的松的昼夜节律并没有影响。因此，光照疗法不一定是通过影响可的松的昼夜节律，也很有可能是通过影响可的松的长期累积水平来减轻SAD患者的症状。为了明确自然光光照时间长短对猕猴毛发可的松累积水平的影响，本研究对长日照组和短日照组的两组猕猴的毛发可的松水平进行了比较。结果表明，短日照组猕猴的毛发可的松水平显著低于长日照组，从而明确了自然光光照时长对正常猕猴毛发可的松累积水平的影响。本研究可能有助于理解SAD中的可的松相关机制，同时有望为阐明光疗法改善SAD症状的机制提供理论依据。
- 自然光光照 /
- 猕猴 /
- HPA轴 /
- 毛发可的松 /
- 季节性情感障碍(SAD)
Abstract: Major depressive disorder (MDD), commonly known as depression, is a mental disease characterized by a core symptom of low mood. It lasts at least two weeks (Badamasi et al., 2019; Wang et al., 2019) and is frequently accompanied by low self-esteem, loss of interest in routinely enjoyable activities, low energy, and unexplained pain (Huey et al., 2018; Park et al., 2012; Post & Warden, 2018; Rice et al., 2019; Xiao et al., 2018). Approximately 2%–8% of adults with MDD commit suicide (Richards & O'Hara, 2014; Strakowski & Nelson, 2015), and around half of suicidal individuals suffer depression or other mood disorders (Bachmann, 2018).
- Sunlight exposure /
- Rhesus monkeys /
- HPA axis /
- Hair cortisol /
- Seasonal affective disorder (SAD)