大肠杆菌PRIBOW与起始位点的统计分析
Escherichia coli DNA Pribow and Transcription Initiation Sites A Statistical Study
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摘要: 通过对大肠杆菌RNA聚合酶识别的44个启动子及其起始位点进行统计分析,估计了PRIBOW的系列范围,计算出它们的信息量。所得结果与真核生物中HUMAN的TATA框进行比较,得到了这两个物种的信息量曲线与不确定值曲线都具有显著差异,尤其在PRIBOW和TATA框与起始位点的对应关系上得到明显不同的结果。PRIBOW与起始位点有比较明显的关系,而HUMAN的TATA框与起始位点的对应关系则不太明确。Abstract: In this paper,a statistical study of PRIBOW and transcription initiation sites in E.coli DNA protein-coding genes was presented.The range over which the two signal sequences extend was assessed,and their information content was evaluated.The results were compared with those obtained from"HUMAN"samples.Statistically significant difference were found for both signals,and were especially for corresponding to the transcription initiation site.