Abstract: The investigation is the first report on chemical compositions of Scolopendra mojiangica Zhang et Chi and comparison of the chemical compositions between S.mojiangica Zhang et Chi and S.subspinipes mutilans L.Koch were made.The contents were dentermined on their water,residues,proteins,free amino acids,microelements,lipid,and volatile fatty acids.The results showed that S.mojiangica contains proteins of 67.20%,residues of 3.95%,water of 3.59%,and lipid of 22.40%,while S.subspinipes mutilans was proteins of 68.80%,residues of 4.80%,water of 3.65%,and lipid of 10.35%,For the results showed that the contents of their main components in the both centipedes,except lipid,almost were the same.The free amino acids,volatile fatty acids,and microelements were compared to be approach.In the determined microelements,harmful elements were less than 1×10-6.lipid in S.mojiangica was different from S.subspinipes mutilans,but the volatile fatty acids were similar.It is possible that those fatty acids combined with other components are different.