Volume 23 Issue 1
Jan.  2002
Turn off MathJax
Article Contents

ZHENG Ping, ZOU Rou-jin, LIU Yi-xun. Possible Involvement of Plasminogen Activator in the Acquirement of Sperm Progressive Motility and the Regulation of PA and PAI-1 mRNA Expressions in Epididymis,Prostate and Seminal Vesical in Rhesus Monkey. Zoological Research, 2002, 23(1): 19-24.
Citation: ZHENG Ping, ZOU Rou-jin, LIU Yi-xun. Possible Involvement of Plasminogen Activator in the Acquirement of Sperm Progressive Motility and the Regulation of PA and PAI-1 mRNA Expressions in Epididymis,Prostate and Seminal Vesical in Rhesus Monkey. Zoological Research, 2002, 23(1): 19-24.

Possible Involvement of Plasminogen Activator in the Acquirement of Sperm Progressive Motility and the Regulation of PA and PAI-1 mRNA Expressions in Epididymis,Prostate and Seminal Vesical in Rhesus Monkey

  • Received Date: 1900-01-01
  • Rev Recd Date: 1900-01-01
  • Publish Date: 2002-02-22
  • Rhesus monkeys were injected 11-T or were performed with unilateral cryptochidism to induce decrease of sperm count and motility.The expressions of tPA,uPA and PAI-1 mRNA in the normal and treated caput,corpus and cauda epididymis,prostate gland and seminal vesicle were examined by in situ hybridization.Results showed that after 9 weeks of 11-T injection,tPA mRNA expression increased in corpus,decreased in caput,seminal vesicle and prostate,while kept consistant in cauda;uPA mRNA expression increased in seminal vesical,decreased in caput,corpus and prostate,but remained unchanged in cauda;PAI-1 mRNA expression increased in prostate,decreased in caput,corpus and seminal vesicle,and no significant change was found in cauda.Unilateral cryptorchidism did not markedly alter the expressions for tPA,uPA and PAI-1 mRNA.These results suggest that 1)uPA produced by caput and corpus epididymis may be involved in the acquirement of sperm progressive motility;2)testosterone,but not other factors from testis or temperature regulate the tPA,uPA and PAI-1 mRNA expressions in caput,corpus epididymis,prostate and seminal vesical in a regionspecific manner.However,the expressions for tPA,uPA and PAI-1 mRNA in cauda epididymis are regulated by none of the above factors.
  • 加载中
  • 加载中
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索

Article Metrics

Article views(2411) PDF downloads(1775) Cited by()

Related
Proportional views

Possible Involvement of Plasminogen Activator in the Acquirement of Sperm Progressive Motility and the Regulation of PA and PAI-1 mRNA Expressions in Epididymis,Prostate and Seminal Vesical in Rhesus Monkey

Abstract: Rhesus monkeys were injected 11-T or were performed with unilateral cryptochidism to induce decrease of sperm count and motility.The expressions of tPA,uPA and PAI-1 mRNA in the normal and treated caput,corpus and cauda epididymis,prostate gland and seminal vesicle were examined by in situ hybridization.Results showed that after 9 weeks of 11-T injection,tPA mRNA expression increased in corpus,decreased in caput,seminal vesicle and prostate,while kept consistant in cauda;uPA mRNA expression increased in seminal vesical,decreased in caput,corpus and prostate,but remained unchanged in cauda;PAI-1 mRNA expression increased in prostate,decreased in caput,corpus and seminal vesicle,and no significant change was found in cauda.Unilateral cryptorchidism did not markedly alter the expressions for tPA,uPA and PAI-1 mRNA.These results suggest that 1)uPA produced by caput and corpus epididymis may be involved in the acquirement of sperm progressive motility;2)testosterone,but not other factors from testis or temperature regulate the tPA,uPA and PAI-1 mRNA expressions in caput,corpus epididymis,prostate and seminal vesical in a regionspecific manner.However,the expressions for tPA,uPA and PAI-1 mRNA in cauda epididymis are regulated by none of the above factors.

ZHENG Ping, ZOU Rou-jin, LIU Yi-xun. Possible Involvement of Plasminogen Activator in the Acquirement of Sperm Progressive Motility and the Regulation of PA and PAI-1 mRNA Expressions in Epididymis,Prostate and Seminal Vesical in Rhesus Monkey. Zoological Research, 2002, 23(1): 19-24.
Citation: ZHENG Ping, ZOU Rou-jin, LIU Yi-xun. Possible Involvement of Plasminogen Activator in the Acquirement of Sperm Progressive Motility and the Regulation of PA and PAI-1 mRNA Expressions in Epididymis,Prostate and Seminal Vesical in Rhesus Monkey. Zoological Research, 2002, 23(1): 19-24.

Catalog

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return