Volume 33 Issue 3
May  2012
Turn off MathJax
Article Contents
SHEN Wen-Ying, REN Gang, ZHU Yao-Rong. Effects of compensatory growth on the levels of IGF-1, IGFBP-1 and expressions of IGF-1 mRNA, IGF-1R mRNA in Carassius auratus gibelio. Zoological Research, 2012, 33(3): 298-303. doi: 10.3724/SP.J.1141.2012.03298
Citation: SHEN Wen-Ying, REN Gang, ZHU Yao-Rong. Effects of compensatory growth on the levels of IGF-1, IGFBP-1 and expressions of IGF-1 mRNA, IGF-1R mRNA in Carassius auratus gibelio. Zoological Research, 2012, 33(3): 298-303. doi: 10.3724/SP.J.1141.2012.03298

Effects of compensatory growth on the levels of IGF-1, IGFBP-1 and expressions of IGF-1 mRNA, IGF-1R mRNA in Carassius auratus gibelio

doi: 10.3724/SP.J.1141.2012.03298
  • Received Date: 2012-02-15
  • Rev Recd Date: 2012-04-18
  • Publish Date: 2012-06-22
  • We studied the effects of starvation and re-feeding on the levels of plasma IGF-1, IGFBP-1 and expressions of hepatic IGF-1 mRNA and muscle IGF-1R mRNA in Carassius auratus gibelio. During the two week starvation period, both the levels of plasma IGF-1 and IGFBP-1 decreased and were significantly lower on day 14 (P<0.05). On the first day of re-feeding, the level of plasma IGF-1 increased sharply, to the level of control group, and had no significant changes for the remaining days. While the level of plasma IGFBP-1 was still greatly lower than that of control group at the first day of re-feeding, it increased significantly higher than that of control group by day 14 (P<0.05). During the starvation period, expression of IGF-1 mRNA in liver decreased, but it was not statistically different from that of the control group (P>0.05). During the early period of re-feeding, the abundance of IGF-1 mRNA was still significantly lower than that of control group (P<0.05), then increased to the level of control group on day 7. IGF-1R mRNA showed a decreasing trend after starvation, and reached a significantly low value on day 3 (P<0.05). After re-feeding, the abundance of IGF-1R mRNA increased to peak at day 14. These results indicate that the higher level of IGFBP-1 in serum and IGF-1R mRNA in muscle after re-feeding could improve the promoting growth effect of IGF-1 to participate in the regulation of compensatory growth.
  • loading
  • [1]
    Chauvigné F, Gabillar JC, Weil C, Rescan PY. 2003. Effect of refeeding on IGFI, IGFII, IGF receptors, FGF2, FGF6, and myostatin mRNA expression in rainbow trout myotomal muscle [J]. Gen Comp Endocrinol, 132(2): 209-215.
    Chen NS, Zhou J, Jin LN, Zhou HY, Ma JZ, Chou XJ. 2010. Effects of fasting on growth and expression abundance of IGF-1 mRNA in largemouth bass (Micropterus salmoides) [J]. J Fish Sci, 17(4): 713-720. [陈乃松, 周洁, 靳利娜, 周恒永, 马建忠, 仇小洁. 2010. 禁食对大口黑鲈生长和肝脏IGF-I mRNA 表达丰度的影响. 中国水 产科学, 17(4): 713-720.]
    Calow P. 1973. On the regulatory nature of individual growth: some observations from freshwater snails [J]. J Zool, 170(4): 415-428.
    Cui Z H, Wang Y, Qin J G. 2006. Compensatory growth of group-held gibel carp, Carassius auratus gibelio (Bloch), following feed deprivation [J]. Aquac Res, 37(3): 313-318.
    Dobson SH, Holmes RM. 1984. Compensatory growth in the rainbow trout, Salmo gairdneri Richardson [J]. J Fish Biol, 25(6): 649-656.
    Duan CA, Phsetakaya EM. 1993. Nutritional regulation of insulin-like growth factor-1 mRNA expression in salmon tissues [J]. J Endocrinol, 139(2): 243-252.
    Duan CM. 1998. Nutritional and developmental regulation of insulin-like growth factors in fish[J]. J Nutr, 128(2): 306S-314S.
    Guler HP, Zapf J, Schmid C, Froesch ER. 1989. Insulin-like growth factors I and II in healthy man. estimations of half-lives and production rates [J].Acta Endocrinol, 121(6): 753-758.
    Hevrøy EM, Azpeleta C, Shimizu M, Lanzén A, Kaiya H, Espe M, Olsvik PA. 2011. Effects of short-term starvation on ghrelin, GH-IGF system, and IGF-binding proteins in Atlantic salmon [J]. Fish Physiol Biochem, 37(1): 217-232.
    Hodgkinson SC, Davis SR, Burleigh BD, Henderson HV, Gluckman PD. 1987. Metabolic clearance rate of insulin-like growth factor-I in fed and starved sheep [J]. J Endocrinol, 115(2): 233-240.
    Hua YM, Lin HR. 2001. Effects of different nutritional status on expression of IGF-1 mRNA in immature common carp liver [J]. Acta Zool Sin, 47(1): 94-100. [华益民, 林浩然. 2001. 营养状况对幼年鲤鱼肝脏IGF-1mRNA 表达的影响. 动物学报, 2001, 47(1): 94-100.]
    Jobling M, Jørgensen EH, Siikavuopio SI. 1993. The influence of previous feeding regime on the compensatory growth response of maturing and immature Arctic charr, Salvelinus alpines [J]. J Fish Biol, 43(3): 409-419.
    Jones JI, Clemmons DR. 1995. Insulin-like growth factors and their binding proteins: biological actions [J]. Endocr Rev, 16(1): 3-34.
    Kyriazakis I, Stamataris C, Emmans GC, Whittemore C T. 1991. The effects of food protein content on the performance of pigs previously given foods with low or moderate protein contents [J]. Anim Prod, 52(1): 165-173.
    Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method [J]. Methods, 25(4): 402-408.
    Miglvas I, Jobling M. 1989. The effects of feeding regime on proximate body composition and patterns of energy deposition in juvenile Arctic charr, Salvelinus alpines [J]. J Fish Biol, 35(1): 1-11.
    Qian X, Cui Y, Xiong B, Yang Y. 2000. Compensatory growth, feed utilization and activity in gibel carp, following feed deprivation [J]. J Fish Biol, 56(1): 228-232.
    Peterson BC, Small BC. 2004. Effects of fasting on circulating IGF-binding proteins, glucose, and cortisol in channel catfish (Ictalurus punctatus) [J]. Domest Anim Endocrinol, 26(3): 231-240.
    Pierce AL, Shimizu M, Beckman BR, Baker DM, Dickhoff WW. 2005.Time course of the GH/IGF axis response to fasting and increased ration in chinook salmon (Oncorhynchus tshawytscha)[J]. Gen Comp Endocrinol, 140(3): 192-202.
    Reimers E, Kjørrefjord AG, Stavøstrand SM. 1993. Compensatory growth and reduced maturation in second sea winter farmed Atlantic salmon following starvation in February and March [J]. J Fish Biol, 43(5): 805-810.
    Ren G, Shou JX, Shen WY. 2010. Effects of starvation and refeeding on growth and ovary development in Crucian Carp Carassius auratus gibelio [J]. Fish Sci, 29(9): 515-518. [任岗, 寿建昕, 沈文英. 2010. 饥饿和恢复投喂对异育银鲫生长和卵巢发育相关指标的影响. 水 产科学, 29(9): 515-518.]
    Shen WY, Zhang LH, Zheng YP, Zhou LQ, Zheng JP. 2003. Effect of starvation on blood composition and ovarion development in Carassius auratus gibelio [J]. Zool Res, 24(6): 441-444. [沈文英, 张利红, 郑永 萍, 周刘琴, 郑建平. 2003. 饥饿对银鲫血液组分和卵巢发育的影 响. 动物学研究, 24(6): 441-444.]
    Shimizu M, Dickey JT, Fukada H, Dickhoff WW. 2005. Salmon serum 22 kDa insulin-like growth factor-binding protein (IGFBP) is IGFBP-1 [J].J Endocrinol, 184(1): 267-276.
    Siharath K, Kelley KM, Bern HA. 1996. A low-molecular-weight (25-kDa) IGF-binding protein is increased with growth inhibition in the fasting striped bass, Morone saxatilis[J]. Gen Comp Endocrinol, 102(3): 307-316.
    Thorpe JE, Tallbot C, Miles MS, Keay DS. 1990. Control of maturation in cultured Atlantic salmon, Salmo salar, in pumped seawater tanks, by restricting food intake [J]. Aquac, 86(2-3): 315-326.
    Tudor GD, O’Rourke PK. 1980. The effect of pre- and post-natal nutrition on the growth of beef cattle Ⅱ, The effect of severe restriction in early post-natal life on growth and feed efficiency during recovery [J]. Aust Agric Res, 31(1): 179-189.
    Turchini GM, Francis DS, De Silva SS. 2007. Finishing diets stimulate compensatory growth: results of a study on Murray cod, Maccullochella peelii peelii [J]. Aqua Nutr, 13(5): 351-360.
    Wilkinson RJ, Porter M, Woolcott H, Longland R, Carragher JF. 2006.Effects of aquaculture related stressors and nutritional restriction on circulating growth factors (GH, IGF-I and IGF-II) in Atlantic salmon and rainbow trout [J]. Comp Biochem Physiol A: Mol Integr Physiol, 145(2): 214-224.
    Wood AW, Duan CM, Bern HA. 2005. Insulin-like growth factor signaling in fish [J]. Int Rev Cytol, 243: 215-285.
  • Relative Articles

    [1] Lei Guo, Yan-Cui Wang, Jun-Jie Mei, Ruo-Tong Ning, Jing-Jing Wang, Jia-Qi Li, Xi Wang, Hui-Wen Zheng, Hai-Tao Fan, Long-Ding Liu. Pulmonary immune cells and inflammatory cytokine dysregulation are associated with mortality of IL-1R1-/-mice infected with influenza virus (H1N1). Zoological Research, 2017, 38(3): 146-154.  doi: 10.24272/j.issn.2095-8137.2017.035
    [2] Qiang CHEN, Xin-Jiang LU, Ming-Yun LI, Jiong CHEN. Molecular cloning, pathologically-correlated expression and functional characterization of the colonystimulating factor 1 receptor (CSF-1R) gene from a teleost, Plecoglossus altivelis. Zoological Research, 2016, 37(2): 96-102.  doi: 10.13918/j.issn.2095-8137.2016.2.96
    [3] Qiong-Ying TANG, Li-Xia SHI, Fei LIU, Dan YU, Huan-Zhang LIU. Evolution and phylogenetic application of the MC1R gene in the Cobitoidea (Teleostei: Cypriniformes). Zoological Research, 2016, 37(5): 281-289.  doi: 10.13918/j.issn.2095-8137.2016.5.281
    [4] . Volume 36, Issue 1 18 January 2015. Zoological Research, 2015, 36(1): 1-63.
    [5] Yu-Mei TIAN, Jie CHEN, Yang TAO, Xia-Yun JIANG, Shu-Ming ZOU. Molecular cloning and function analysis of insulin-like growth factor-binding protein 1a in blunt snout bream (Megalobrama amblycephala). Zoological Research, 2014, 35(4): 300-306.  doi: 10.13918/j.issn.2095-8137.2014.4.300
    [6] LI Pei-Lu, CHEN Qian-Qian, ZHANG Chi-Yu. SAMHD1— A HIV-1 restriction factor derived from myeloid lineage monocytes. Zoological Research, 2012, 33(5): 537-541.  doi: 10.3724/SP.J.1141.2012.05537
    [7] ZHANG Ying, YU Jian-Feng, YANG Li, WANG Xing-Guo, GU Zhi-Liang. Cloning and characterization of Caveolin-1 gene in pigeon,Columba livia domestica. Zoological Research, 2010, 31(5): 476-482.  doi: 10.3724/SP.J.1141.2010.05476
    [8] ZHOU Liang, YANG Jun-Xing. Screening and Identification of Mouse Bicc1 RNAi. Zoological Research, 2010, 31(1): 84-88.  doi: 10.3724/SP.J.1141. 2010.01077
    [9] ZHOU Hui-fang, LU Xiao-peng, SUN Zheng-hua, GUO Yan, ZHANG Hua-tang. Establishment and Characterization of THP-1 Cell Model Stably Expressing HIV-1 Auxiliary Protein Rev. Zoological Research, 2008, 29(4): 421-426.  doi: 10.3724/SP.J.1141.2008.04421
    [10] MA Dong-mei, ZHU Hua-ping, GUI Jian-fang. Molecular Cloning and Expression Characterization of Prox1 in Goldfish (Carassius auratus) Eye Development. Zoological Research, 2007, 28(6): 589-596.
    [11] WANG Jian-hua , OUYANG Dong-yun, WANG Yuan-yuan, ZHENG Yong-tang , *. Progress in Anti-HIV-1 Actions of Ribosome Inactivating Proteins. Zoological Research, 2006, 27(5): 541-548.
    [12] ZHANG Chi-yu. Phenotype and Cellular Tropism of Human Immunodeficiency Virus Type 1. Zoological Research, 2004, 25(4): 363-368.
    [13] ZHAO Tong-biao, ZHAO Xin-quan, CHANG Zhi-jie, SUN Ping, XU Shi-xiao, ZHAO Wei. Tissue Specific Expression of Plateau Pikas (Ochotona curzoniae) HIF-1α mRNA Under Normal Oxygen. Zoological Research, 2004, 25(2): 132-136.
    [14] LIU Xu-sheng, LIANG Bing, ZHANG Shu-yi. cDNA Cloning,Tissue Distribution and mRNA Transcription of DMRT1 Gene in the Protandrous Black Porgy Acanthopagrus schlegeli. Zoological Research, 2004, 25(2): 158-161.
    [15] SHEN Wen-ying, ZHANG Li-hong, ZHENG Yong-ping, ZHOU Liu-qin, ZHENG Jian-ping. Effects of Starvation on Blood Composition and Ovarian Development in Carassius auratus gibelio. Zoological Research, 2003, 24(6): 441-444.
    [16] PENG Xian-wen, ZHONG Guang-hui, ZHENG Yu-cai, MAO Yong-jiang, WANG Yong, JIANG Ming-feng. Genetic Polymorphism of Epithelial Mucin,MUC1,in Milk of Goats. Zoological Research, 2002, 23(1): 15-18.
    [17] ZHENG Ping, ZOU Rou-jin, LIU Yi-xun. Possible Involvement of Plasminogen Activator in the Acquirement of Sperm Progressive Motility and the Regulation of PA and PAI-1 mRNA Expressions in Epididymis,Prostate and Seminal Vesical in Rhesus Monkey. Zoological Research, 2002, 23(1): 19-24.
    [18] ZHOU Li, LIU Jin-Xia, GUI Jian-Fang. Preliminary Investigation on Genetic Diversity of Gynogenetic Silver Crucian Carp (Carassius auratus gibelio Bloch) Detected by Microsatellite DNA. Zoological Research, 2001, 22(4): 257-264.
    [19] ZHENG Yuan-Lin, HAN Zheng-Kang, CHEN Jie, AI Xiao-Jie, LIU Gen-Tao. Effects of Clenbuterol on IGF-Ⅰ,GH and Insulin Level of Hepatic Blood in Sheep. Zoological Research, 2001, 22(3): 246-249.
    [20] LI Hong-fang, WANG Long-de, QIN Xiao-min. Effect of Prostaglandin E1 On Rat's Antral Myoelectric Activity. Zoological Research, 1998, 19(6): 434-438.
  • 加载中


    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (1897) PDF downloads(1711) Cited by()
    Proportional views


    DownLoad:  Full-Size Img  PowerPoint