Volume 33 Issue 3
May  2012
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SHEN Wen-Ying, REN Gang, ZHU Yao-Rong. Effects of compensatory growth on the levels of IGF-1, IGFBP-1 and expressions of IGF-1 mRNA, IGF-1R mRNA in Carassius auratus gibelio. Zoological Research, 2012, 33(3): 298-303. doi: 10.3724/SP.J.1141.2012.03298
Citation: SHEN Wen-Ying, REN Gang, ZHU Yao-Rong. Effects of compensatory growth on the levels of IGF-1, IGFBP-1 and expressions of IGF-1 mRNA, IGF-1R mRNA in Carassius auratus gibelio. Zoological Research, 2012, 33(3): 298-303. doi: 10.3724/SP.J.1141.2012.03298

Effects of compensatory growth on the levels of IGF-1, IGFBP-1 and expressions of IGF-1 mRNA, IGF-1R mRNA in Carassius auratus gibelio

doi: 10.3724/SP.J.1141.2012.03298
  • Received Date: 2012-02-15
  • Rev Recd Date: 2012-04-18
  • Publish Date: 2012-06-22
  • We studied the effects of starvation and re-feeding on the levels of plasma IGF-1, IGFBP-1 and expressions of hepatic IGF-1 mRNA and muscle IGF-1R mRNA in Carassius auratus gibelio. During the two week starvation period, both the levels of plasma IGF-1 and IGFBP-1 decreased and were significantly lower on day 14 (P<0.05). On the first day of re-feeding, the level of plasma IGF-1 increased sharply, to the level of control group, and had no significant changes for the remaining days. While the level of plasma IGFBP-1 was still greatly lower than that of control group at the first day of re-feeding, it increased significantly higher than that of control group by day 14 (P<0.05). During the starvation period, expression of IGF-1 mRNA in liver decreased, but it was not statistically different from that of the control group (P>0.05). During the early period of re-feeding, the abundance of IGF-1 mRNA was still significantly lower than that of control group (P<0.05), then increased to the level of control group on day 7. IGF-1R mRNA showed a decreasing trend after starvation, and reached a significantly low value on day 3 (P<0.05). After re-feeding, the abundance of IGF-1R mRNA increased to peak at day 14. These results indicate that the higher level of IGFBP-1 in serum and IGF-1R mRNA in muscle after re-feeding could improve the promoting growth effect of IGF-1 to participate in the regulation of compensatory growth.
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  • [1] Chauvigné F, Gabillar JC, Weil C, Rescan PY. 2003. Effect of refeeding on IGFI, IGFII, IGF receptors, FGF2, FGF6, and myostatin mRNA expression in rainbow trout myotomal muscle [J]. Gen Comp Endocrinol, 132(2): 209-215.
    [2] Chen NS, Zhou J, Jin LN, Zhou HY, Ma JZ, Chou XJ. 2010. Effects of fasting on growth and expression abundance of IGF-1 mRNA in largemouth bass (Micropterus salmoides) [J]. J Fish Sci, 17(4): 713-720. [陈乃松, 周洁, 靳利娜, 周恒永, 马建忠, 仇小洁. 2010. 禁食对大口黑鲈生长和肝脏IGF-I mRNA 表达丰度的影响. 中国水 产科学, 17(4): 713-720.]
    [3] Calow P. 1973. On the regulatory nature of individual growth: some observations from freshwater snails [J]. J Zool, 170(4): 415-428.
    [4] Cui Z H, Wang Y, Qin J G. 2006. Compensatory growth of group-held gibel carp, Carassius auratus gibelio (Bloch), following feed deprivation [J]. Aquac Res, 37(3): 313-318.
    [5] Dobson SH, Holmes RM. 1984. Compensatory growth in the rainbow trout, Salmo gairdneri Richardson [J]. J Fish Biol, 25(6): 649-656.
    [6] Duan CA, Phsetakaya EM. 1993. Nutritional regulation of insulin-like growth factor-1 mRNA expression in salmon tissues [J]. J Endocrinol, 139(2): 243-252.
    [7] Duan CM. 1998. Nutritional and developmental regulation of insulin-like growth factors in fish[J]. J Nutr, 128(2): 306S-314S.
    [8] Guler HP, Zapf J, Schmid C, Froesch ER. 1989. Insulin-like growth factors I and II in healthy man. estimations of half-lives and production rates [J].Acta Endocrinol, 121(6): 753-758.
    [9] Hevrøy EM, Azpeleta C, Shimizu M, Lanzén A, Kaiya H, Espe M, Olsvik PA. 2011. Effects of short-term starvation on ghrelin, GH-IGF system, and IGF-binding proteins in Atlantic salmon [J]. Fish Physiol Biochem, 37(1): 217-232.
    [10] Hodgkinson SC, Davis SR, Burleigh BD, Henderson HV, Gluckman PD. 1987. Metabolic clearance rate of insulin-like growth factor-I in fed and starved sheep [J]. J Endocrinol, 115(2): 233-240.
    [11] Hua YM, Lin HR. 2001. Effects of different nutritional status on expression of IGF-1 mRNA in immature common carp liver [J]. Acta Zool Sin, 47(1): 94-100. [华益民, 林浩然. 2001. 营养状况对幼年鲤鱼肝脏IGF-1mRNA 表达的影响. 动物学报, 2001, 47(1): 94-100.]
    [12] Jobling M, Jørgensen EH, Siikavuopio SI. 1993. The influence of previous feeding regime on the compensatory growth response of maturing and immature Arctic charr, Salvelinus alpines [J]. J Fish Biol, 43(3): 409-419.
    [13] Jones JI, Clemmons DR. 1995. Insulin-like growth factors and their binding proteins: biological actions [J]. Endocr Rev, 16(1): 3-34.
    [14] Kyriazakis I, Stamataris C, Emmans GC, Whittemore C T. 1991. The effects of food protein content on the performance of pigs previously given foods with low or moderate protein contents [J]. Anim Prod, 52(1): 165-173.
    [15] Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method [J]. Methods, 25(4): 402-408.
    [16] Miglvas I, Jobling M. 1989. The effects of feeding regime on proximate body composition and patterns of energy deposition in juvenile Arctic charr, Salvelinus alpines [J]. J Fish Biol, 35(1): 1-11.
    [17] Qian X, Cui Y, Xiong B, Yang Y. 2000. Compensatory growth, feed utilization and activity in gibel carp, following feed deprivation [J]. J Fish Biol, 56(1): 228-232.
    [18] Peterson BC, Small BC. 2004. Effects of fasting on circulating IGF-binding proteins, glucose, and cortisol in channel catfish (Ictalurus punctatus) [J]. Domest Anim Endocrinol, 26(3): 231-240.
    [19] Pierce AL, Shimizu M, Beckman BR, Baker DM, Dickhoff WW. 2005.Time course of the GH/IGF axis response to fasting and increased ration in chinook salmon (Oncorhynchus tshawytscha)[J]. Gen Comp Endocrinol, 140(3): 192-202.
    [20] Reimers E, Kjørrefjord AG, Stavøstrand SM. 1993. Compensatory growth and reduced maturation in second sea winter farmed Atlantic salmon following starvation in February and March [J]. J Fish Biol, 43(5): 805-810.
    [21] Ren G, Shou JX, Shen WY. 2010. Effects of starvation and refeeding on growth and ovary development in Crucian Carp Carassius auratus gibelio [J]. Fish Sci, 29(9): 515-518. [任岗, 寿建昕, 沈文英. 2010. 饥饿和恢复投喂对异育银鲫生长和卵巢发育相关指标的影响. 水 产科学, 29(9): 515-518.]
    [22] Shen WY, Zhang LH, Zheng YP, Zhou LQ, Zheng JP. 2003. Effect of starvation on blood composition and ovarion development in Carassius auratus gibelio [J]. Zool Res, 24(6): 441-444. [沈文英, 张利红, 郑永 萍, 周刘琴, 郑建平. 2003. 饥饿对银鲫血液组分和卵巢发育的影 响. 动物学研究, 24(6): 441-444.]
    [23] Shimizu M, Dickey JT, Fukada H, Dickhoff WW. 2005. Salmon serum 22 kDa insulin-like growth factor-binding protein (IGFBP) is IGFBP-1 [J].J Endocrinol, 184(1): 267-276.
    [24] Siharath K, Kelley KM, Bern HA. 1996. A low-molecular-weight (25-kDa) IGF-binding protein is increased with growth inhibition in the fasting striped bass, Morone saxatilis[J]. Gen Comp Endocrinol, 102(3): 307-316.
    [25] Thorpe JE, Tallbot C, Miles MS, Keay DS. 1990. Control of maturation in cultured Atlantic salmon, Salmo salar, in pumped seawater tanks, by restricting food intake [J]. Aquac, 86(2-3): 315-326.
    [26] Tudor GD, O’Rourke PK. 1980. The effect of pre- and post-natal nutrition on the growth of beef cattle Ⅱ, The effect of severe restriction in early post-natal life on growth and feed efficiency during recovery [J]. Aust Agric Res, 31(1): 179-189.
    [27] Turchini GM, Francis DS, De Silva SS. 2007. Finishing diets stimulate compensatory growth: results of a study on Murray cod, Maccullochella peelii peelii [J]. Aqua Nutr, 13(5): 351-360.
    [28] Wilkinson RJ, Porter M, Woolcott H, Longland R, Carragher JF. 2006.Effects of aquaculture related stressors and nutritional restriction on circulating growth factors (GH, IGF-I and IGF-II) in Atlantic salmon and rainbow trout [J]. Comp Biochem Physiol A: Mol Integr Physiol, 145(2): 214-224.
    [29] Wood AW, Duan CM, Bern HA. 2005. Insulin-like growth factor signaling in fish [J]. Int Rev Cytol, 243: 215-285.
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Effects of compensatory growth on the levels of IGF-1, IGFBP-1 and expressions of IGF-1 mRNA, IGF-1R mRNA in Carassius auratus gibelio

doi: 10.3724/SP.J.1141.2012.03298

Abstract: We studied the effects of starvation and re-feeding on the levels of plasma IGF-1, IGFBP-1 and expressions of hepatic IGF-1 mRNA and muscle IGF-1R mRNA in Carassius auratus gibelio. During the two week starvation period, both the levels of plasma IGF-1 and IGFBP-1 decreased and were significantly lower on day 14 (P<0.05). On the first day of re-feeding, the level of plasma IGF-1 increased sharply, to the level of control group, and had no significant changes for the remaining days. While the level of plasma IGFBP-1 was still greatly lower than that of control group at the first day of re-feeding, it increased significantly higher than that of control group by day 14 (P<0.05). During the starvation period, expression of IGF-1 mRNA in liver decreased, but it was not statistically different from that of the control group (P>0.05). During the early period of re-feeding, the abundance of IGF-1 mRNA was still significantly lower than that of control group (P<0.05), then increased to the level of control group on day 7. IGF-1R mRNA showed a decreasing trend after starvation, and reached a significantly low value on day 3 (P<0.05). After re-feeding, the abundance of IGF-1R mRNA increased to peak at day 14. These results indicate that the higher level of IGFBP-1 in serum and IGF-1R mRNA in muscle after re-feeding could improve the promoting growth effect of IGF-1 to participate in the regulation of compensatory growth.

SHEN Wen-Ying, REN Gang, ZHU Yao-Rong. Effects of compensatory growth on the levels of IGF-1, IGFBP-1 and expressions of IGF-1 mRNA, IGF-1R mRNA in Carassius auratus gibelio. Zoological Research, 2012, 33(3): 298-303. doi: 10.3724/SP.J.1141.2012.03298
Citation: SHEN Wen-Ying, REN Gang, ZHU Yao-Rong. Effects of compensatory growth on the levels of IGF-1, IGFBP-1 and expressions of IGF-1 mRNA, IGF-1R mRNA in Carassius auratus gibelio. Zoological Research, 2012, 33(3): 298-303. doi: 10.3724/SP.J.1141.2012.03298
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