Volume 39 Issue 6
Nov.  2018
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Yang Yang, Adeniyi C. Adeola, Hai-Bing Xie, Ya-Ping Zhang. Genomic and transcriptomic analyses reveal selection of genes for puberty in Bama Xiang pigs. Zoological Research, 2018, 39(6): 424-430. doi: 10.24272/j.issn.2095-8137.2018.068
Citation: Yang Yang, Adeniyi C. Adeola, Hai-Bing Xie, Ya-Ping Zhang. Genomic and transcriptomic analyses reveal selection of genes for puberty in Bama Xiang pigs. Zoological Research, 2018, 39(6): 424-430. doi: 10.24272/j.issn.2095-8137.2018.068

Genomic and transcriptomic analyses reveal selection of genes for puberty in Bama Xiang pigs

doi: 10.24272/j.issn.2095-8137.2018.068
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  • Corresponding author: Hai-Bing Xie, Ya-Ping Zhang,E-mail:xiehb@mail.kiz.ac.cn; zhangyp@mail.kiz.ac.cn
  • Publish Date: 2018-11-18
  • The Bama Xiang pig (BMX) is a famous early-maturing Chinese indigenous breed with a two-end black coat. To uncover the genetic basis of the BMX phenotype, we conducted comparative genomic analyses between BMX and East Asian wild boars and Laiwu pigs, respectively. Genes under positive selection were enriched in pathways associated with gonadal hormone and melanin synthesis, consistent with the phenotypic changes observed during development in BMX pigs. We also performed differentially expressed gene analysis based on RNA-seq data from pituitary tissues of BMX and Large White pigs. The CTTNBP2NL, FRS2, KANK4, and KATNAL1 genes were under selection and exhibited expressional changes in the pituitary tissue, which may affect BMX pig puberty. Our study demonstrated the positive selection of early maturity in the development of BMX pigs and advances our knowledge on the role of regulatory elements in puberty evolution in pigs.
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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Genomic and transcriptomic analyses reveal selection of genes for puberty in Bama Xiang pigs

doi: 10.24272/j.issn.2095-8137.2018.068
Funds:   
    Corresponding author: Hai-Bing Xie, Ya-Ping Zhang,E-mail:xiehb@mail.kiz.ac.cn; zhangyp@mail.kiz.ac.cn

Abstract: The Bama Xiang pig (BMX) is a famous early-maturing Chinese indigenous breed with a two-end black coat. To uncover the genetic basis of the BMX phenotype, we conducted comparative genomic analyses between BMX and East Asian wild boars and Laiwu pigs, respectively. Genes under positive selection were enriched in pathways associated with gonadal hormone and melanin synthesis, consistent with the phenotypic changes observed during development in BMX pigs. We also performed differentially expressed gene analysis based on RNA-seq data from pituitary tissues of BMX and Large White pigs. The CTTNBP2NL, FRS2, KANK4, and KATNAL1 genes were under selection and exhibited expressional changes in the pituitary tissue, which may affect BMX pig puberty. Our study demonstrated the positive selection of early maturity in the development of BMX pigs and advances our knowledge on the role of regulatory elements in puberty evolution in pigs.

Yang Yang, Adeniyi C. Adeola, Hai-Bing Xie, Ya-Ping Zhang. Genomic and transcriptomic analyses reveal selection of genes for puberty in Bama Xiang pigs. Zoological Research, 2018, 39(6): 424-430. doi: 10.24272/j.issn.2095-8137.2018.068
Citation: Yang Yang, Adeniyi C. Adeola, Hai-Bing Xie, Ya-Ping Zhang. Genomic and transcriptomic analyses reveal selection of genes for puberty in Bama Xiang pigs. Zoological Research, 2018, 39(6): 424-430. doi: 10.24272/j.issn.2095-8137.2018.068

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