Volume 40 Issue 2
Mar.  2019
Turn off MathJax
Article Contents
Yan-Fang Cui, Feng-Jie Wang, Lei Yu, Hua-Hu Ye, Gui-Bo Yang. Metagenomic comparison of the rectal microbiota between rhesus macaques (Macaca mulatta) and cynomolgus macaques (Macaca fascicularis). Zoological Research, 2019, 40(2): 89-93. doi: 10.24272/j.issn.2095-8137.2018.061
Citation: Yan-Fang Cui, Feng-Jie Wang, Lei Yu, Hua-Hu Ye, Gui-Bo Yang. Metagenomic comparison of the rectal microbiota between rhesus macaques (Macaca mulatta) and cynomolgus macaques (Macaca fascicularis). Zoological Research, 2019, 40(2): 89-93. doi: 10.24272/j.issn.2095-8137.2018.061

Metagenomic comparison of the rectal microbiota between rhesus macaques (Macaca mulatta) and cynomolgus macaques (Macaca fascicularis)

doi: 10.24272/j.issn.2095-8137.2018.061
Funds:   
More Information
  • Corresponding author: Gui-Bo Yang,E-mail:guiboyang@chinaaids.cn
  • Publish Date: 2019-03-18
  • Rhesus macaques (Macaca mulatta) and cynomolgus macaques (Macaca fascicularis) are frequently used in establishing animal models for human diseases. To determine the differences in gut microbiota between these species, rectal swabs from 20 rhesus macaques and 21 cynomolgus macaques were collected, and the microbial composition was examined by deep sequencing of the 16S rRNA gene. We found that the rectal microbiota of cynomolgus macaques exhibited significantly higher alpha diversity than that of rhesus macaques, although the observed number of operational taxonomic units (OTUs) was almost the same. The dominant taxa at both the phylum and genus levels were similar between the two species, although the relative abundances of these dominant taxa were significantly different between them. Phylogenetic Investigation of Communities by Reconstruction of Unobserved States (PICRUSt) showed significant differences in the functional components between the microbiota of the two species, in particular the lipopolysaccharide (LPS) synthesis proteins. The above data indicated significant differences in microbial composition and function between these two closely related macaque species, which should be taken into consideration in the future selection of these animals for disease models.
  • loading
  • Relative Articles

    [1] Hong-Zhe Li, Nan Li, Jing-Jing Wang, Heng Li, Xing Huang, Lei Guo, Hui-Wen Zheng, Zhan-Long He, Yuan Zhao, Ze-Ning Yang, Hai-Tao Fan, Man-Man Chu, Jin-Xi Yang, Qiong-Wen Wu, Long-Ding Liu. Dysbiosis of gut microbiome affecting small intestine morphology and immune balance: a rhesus macaque model. Zoological Research, 2020, 41(1): 20-31.  doi: 10.24272/j.issn.2095-8137.2020.004
    [2] Tian-Zhang Song, Hong-Yi Zheng, Jian-Bao Han, Lin Jin, Xiang Yang, Feng-Liang Liu, Rong-Hua Luo, Ren-Rong Tian, Hou-Rong Cai, Xiao-Li Feng, Chao Liu, Ming-Hua Li, Yong-Tang Zheng. Delayed severe cytokine storm and immune cell infiltration in SARS-CoV-2-infected aged Chinese rhesus macaques. Zoological Research, 2020, 41(5): 503-516.  doi: 10.24272/j.issn.2095-8137.2020.202
    [3] Xue-Hui Wang, Tian-Zhang Song, Lei Li, Ren-Rong Tian, Yong-Tang Zheng. Successful implementation of intestinal resection and anastomosis in non-human primates suggests the possibility of longitudinal intestinal research. Zoological Research, 2020, 41(4): 449-454.  doi: 10.24272/j.issn.2095-8137.2020.049
    [4] Qi Jiang, Dong-Po Xia, Xi Wang, Dao Zhang, Bing-Hua Sun, Jin-Hua Li. Interchange between grooming and infant handling in female Tibetan macaques (Macaca thibetana). Zoological Research, 2019, 40(2): 139-145.  doi: 10.24272/j.issn.2095-8137.2018.049
    [5] Jin-Bo Xiong, Li Nie, Jiong Chen. Current understanding on the roles of gut microbiota in fish disease and immunity. Zoological Research, 2019, 40(2): 70-76.  doi: 10.24272/j.issn.2095-8137.2018.069
    [6] Dong Li, Feng-Jie Wang, Lei Yu, Wen-Rong Yao, Yan-Fang Cui, Gui-Bo Yang. Expression of pIgR in the tracheal mucosa of SHIV/SIV-infected rhesus macaques. Zoological Research, 2017, 38(1): 44-48.  doi: 10.13918/j.issn.2095-8137.2017.007
    [7] Lin ZHU, Ai-Hua LEI, Hong-Yi ZHENG, Long-Bao LYU, Zhi-Gang ZHANG, Yong-Tang ZHENG. Longitudinal analysis reveals characteristically high proportions of bacterial vaginosis-associated bacteria and temporal variability of vaginal microbiota in northern pig-tailed macaques (Macaca leonina). Zoological Research, 2015, 36(5): 285-298.  doi: 10.13918/j.issn.2095-8137.2015.5.285
    [8] Briana BAUER, Lori K. SHEERAN, Megan D. MATHESON, Jin-Hua LI, R. Steven WAGNER. Male Tibetan macaques’(Macaca thibetana) choice of infant bridging partners. Zoological Research, 2014, 35(3): 222-230.  doi: 10.11813/j.issn.0254-5853.2014.3.222
    [9] Yin MO, Fang CHAO, Ming SONG, Ci-Rong LIU, Hui-Lang LIU, Xi-Ying QIAN, Xu-Dong ZHAO. Parameter comparison of white matter diffusion tensor imaging (DTI) in rhesus macaques (Macaca mulatta). Zoological Research, 2014, 35(3): 182-185.  doi: 10.11813/j.issn.0254-5853.2014.3.182
    [10] Ai-Hua LEI, Wei PANG, Gao-Hong ZHANG, Yong-Tang ZHENG. Use and research of pigtailed macaques in nonhuman primate HIV/AIDS models. Zoological Research, 2013, 34(2): 77-88.  doi: 10.3724/SP.J.1141.2013.02077
    [11] Yu-Qi ZHAO, Gong-Hua LI, Jing-Fei HUANG. Comparative systems biology between human and animal models based on next-generation sequencing methods. Zoological Research, 2013, 34(E2): 13335-E.  doi: 10.3724/SP.J.1141.2013.E02E35
    [12] Dong-Dong QIN, Joshua Dominic Rizak, Xiao-Li FENG, Xun-Xun CHU, Shang-Chuan YANG, Chun-Lu LI, Long-Bao LV, Yuan-Ye MA, Xin-Tian HU. Social rank and cortisol among female rhesus macaques (Macaca mulatta). Zoological Research, 2013, 34(E2): 13342-E.  doi: 10.3724/SP.J.1141.2013.E02E42
    [13] XIA Dong-Po, LI Jin-Hua, ZHU Yong, SUN Bing-Hua, Lori K SHEERAN, Megan D MATHESON. Seasonal variation and synchronization of sexual behaviors in free-ranging male Tibetan macaques (Macaca thibetana) at Huangshan, China. Zoological Research, 2010, 31(5): 509-515.  doi: 10.3724/SP.J.1141.2010.05509
    [14] Cyril C GRUETER, LI Da-Yong, FENG Shun-Kai, REN Bao-Ping. Niche partitioning between sympatric rhesus macaques and Yunnan snub-nosed monkeys at Baimaxueshan Nature Reserve, China. Zoological Research, 2010, 31(5): 516-522.  doi: 10.3724/SP.J.1141.2010.05516
    [15] PAN Ru-liang. Dental Variation Among Asian Colobines, with Specific Reference to the Macaques on the Same Continent. Zoological Research, 2007, 28(6): 569-579.
    [16] PAN Ru-Lian, Charles Oxnard. Craniodental Variation of Macaques (Macaca):Size,Function and Phylogeny. Zoological Research, 2000, 21(4): 308-322.
    [17] CUI Qing-hua, ZHAO Qi-Kun. Supplementary Observation on Male-Infant Behaviors in Tibetan Macaques At Mount Emei. Zoological Research, 1999, 20(3): 196-200.
    [18] YANG Shang-chuan, JI Wei-zhi, CHEN Jian-chun, SHANG En-yuan, ZOU Ru-jin. The Use of Improved Penile Electroejaculation in Rhesus,Tibetan and Assamese Macaques and Study on the Parameters of Their Semen. Zoological Research, 1994, 15(1): 77-83.
    [19] ZHANG Ya-ping, SHI Li-ming. Preparation and Restriction-Enzyme Analysis of Mitochondrial DNA From Brain Tissue of Macaques. Zoological Research, 1992, 13(2): 161-164.
    [20] SONG Bao-yun, BEN Kun-long, DAI Wei, ZHOU Ru-jia. Studies on Lymphocyte Subpopulations in Primates Ⅱ.Nonspecific Esterase Activity of Peripheral Blood Lymphocytes of Macaques. Zoological Research, 1983, 4(3): 261-266.
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (1200) PDF downloads(711) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return