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Volume 38 Issue 6
Nov.  2017
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Article Navigation >  Zoological Research  > 2017  >  38(6): 317-320
Jie Zhang, Guo-Hua Feng, Chun-Yan Zou, Pin-Can Su, Huai-E Liu, Zhao-Qing Yang. Overview of the improvement of the ring-stage survival assay-a novel phenotypic assay for the detection of artemisinin-resistant Plasmodium falciparum. Zoological Research, 2017, 38(6): 317-320. doi: 10.24272/j.issn.2095-8137.2017.075
Citation: Jie Zhang, Guo-Hua Feng, Chun-Yan Zou, Pin-Can Su, Huai-E Liu, Zhao-Qing Yang. Overview of the improvement of the ring-stage survival assay-a novel phenotypic assay for the detection of artemisinin-resistant Plasmodium falciparum. Zoological Research, 2017, 38(6): 317-320. doi: 10.24272/j.issn.2095-8137.2017.075
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Overview of the improvement of the ring-stage survival assay-a novel phenotypic assay for the detection of artemisinin-resistant Plasmodium falciparum

doi: 10.24272/j.issn.2095-8137.2017.075

  • 1 Department of Pathogen Biology and Immunology, Kunming Medical University, Kunming Yunnan 650500, China;

  • 2 Biomedical Engineering Research Center, Kunming Medical University, Kunming Yunnan 650500, China;

  • 3 Guangxi Zhuang Autonomous Region People's Hospital, Nanning Guangxi 530021, China;

  • 4 Transfusion Medicine Research Department, Yunnan Kunming Blood Center, Kunming Yunnan 650500, China;

  • 5 Department of Infectious Diseases, The First Affiliated Hospital, Kunming Medical University, Kunming Yunnan 650032, China

Funds:  This study was funded by the National Natural Science Foundation of China (31260508, U1202226) and grants of Doctor Newcomer Scholarship from Yunnan province
More Information
  • Corresponding author: Zhao-Qing Yang,E-mail:zhaoqing92@hotmail.com
  • Received Date: 2017-10-11
  • Rev Recd Date: 2017-11-10
  • Publish Date: 2017-11-18
    Abstract
  • Artemisinin resistance in Plasmodium falciparum threatens the remarkable efficacy of artemisinin-based combination therapies worldwide. Thus, greater insight into the resistance mechanism using monitoring tools is essential. The ring-stage survival assay is used for phenotyping artemisinin-resistance or decreased artemisinin sensitivity. Here, we review the progress of this measurement assay and explore its limitations and potential applications.
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