Volume 5 Issue 2
Mar.  1984
Turn off MathJax
Article Contents

LI Jing-yan, CHEN Yun-he, ZHOU Xing-liang, ZHENG Zi-xiu. Immunoprotective Activity of Ribosomal Preparation From Poisonous Escherichia coli,the Pathogen of Piglet Dysentery. Zoological Research, 1984, 5(2): 169-174.
Citation: LI Jing-yan, CHEN Yun-he, ZHOU Xing-liang, ZHENG Zi-xiu. Immunoprotective Activity of Ribosomal Preparation From Poisonous Escherichia coli,the Pathogen of Piglet Dysentery. Zoological Research, 1984, 5(2): 169-174.

Immunoprotective Activity of Ribosomal Preparation From Poisonous Escherichia coli,the Pathogen of Piglet Dysentery

  • Received Date: 1900-01-01
  • Rev Recd Date: 1900-01-01
  • Publish Date: 1984-05-22
  • A virulent strain of Escherichia coli had been isolated and found to be the pathogen of piglet dysentery by Mr.Li Xue-liang (Yunnan Institute of Animal Husbandary and Veterinary Medicine).When 6×107 living bacteria of the virulent strain were injected subcutaneously into each mouse,all the injected mice would be killed.Ribosomal preparations were isolated from disrupted cells by a modification of the ammonium sulfate precipitation method described by C.G.Kurland (1966),omitting the ultracentrifugation step.The ribosomal preparation was proved to be highly immunogenic for mice and immunization with the preparation elicited significant protective immunity.The effect was obvious when mice immunized subcutaneously with ribosomal preparation without adjuvant were challenged subcutaneously with 2-2.4×108 living bacteria two weeks after immunization.
  • 加载中
  • 加载中
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索

Article Metrics

Article views(1457) PDF downloads(1852) Cited by()

Related
Proportional views

Immunoprotective Activity of Ribosomal Preparation From Poisonous Escherichia coli,the Pathogen of Piglet Dysentery

Abstract: A virulent strain of Escherichia coli had been isolated and found to be the pathogen of piglet dysentery by Mr.Li Xue-liang (Yunnan Institute of Animal Husbandary and Veterinary Medicine).When 6×107 living bacteria of the virulent strain were injected subcutaneously into each mouse,all the injected mice would be killed.Ribosomal preparations were isolated from disrupted cells by a modification of the ammonium sulfate precipitation method described by C.G.Kurland (1966),omitting the ultracentrifugation step.The ribosomal preparation was proved to be highly immunogenic for mice and immunization with the preparation elicited significant protective immunity.The effect was obvious when mice immunized subcutaneously with ribosomal preparation without adjuvant were challenged subcutaneously with 2-2.4×108 living bacteria two weeks after immunization.

LI Jing-yan, CHEN Yun-he, ZHOU Xing-liang, ZHENG Zi-xiu. Immunoprotective Activity of Ribosomal Preparation From Poisonous Escherichia coli,the Pathogen of Piglet Dysentery. Zoological Research, 1984, 5(2): 169-174.
Citation: LI Jing-yan, CHEN Yun-he, ZHOU Xing-liang, ZHENG Zi-xiu. Immunoprotective Activity of Ribosomal Preparation From Poisonous Escherichia coli,the Pathogen of Piglet Dysentery. Zoological Research, 1984, 5(2): 169-174.

Catalog

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return