Hao Dai, Qi-Qi Jin, Lin Li, Luo-Nan Chen. 2020: Reconstructing gene regulatory networks in single-cell transcriptomic data analysis. Zoological Research, 41(6): 599-604. DOI: 10.24272/j.issn.2095-8137.2020.215
Citation: Hao Dai, Qi-Qi Jin, Lin Li, Luo-Nan Chen. 2020: Reconstructing gene regulatory networks in single-cell transcriptomic data analysis. Zoological Research, 41(6): 599-604. DOI: 10.24272/j.issn.2095-8137.2020.215

Reconstructing gene regulatory networks in single-cell transcriptomic data analysis

  • Gene regulatory networks play pivotal roles in our understanding of biological processes/mechanisms at the molecular level. Many studies have developed sample-specific or cell-type-specific gene regulatory networks from single-cell transcriptomic data based on a large amount of cell samples. Here, we review the state-of-the-art computational algorithms and describe various applications of gene regulatory networks in biological studies.
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