• 中文核心期刊要目总览
  • 中国科技核心期刊
  • 中国科学引文数据库(CSCD)
  • 中国科技论文与引文数据库(CSTPCD)
  • 中国学术期刊文摘数据库(CSAD)
  • 中国学术期刊(网络版)(CNKI)
  • 中文科技期刊数据库
  • 万方数据知识服务平台
  • 中国超星期刊域出版平台
  • 国家科技学术期刊开放平台
  • 荷兰文摘与引文数据库(SCOPUS)
  • 日本科学技术振兴机构数据库(JST)
秦冬冬, 冯书斐, 张飞宇, 王纳, 孙文杰, 周引, 熊腾芳, 徐仙来, 杨晓婷, 张祥, 朱雪, 胡新天, 熊磊, 刘芸, 陈永昌. 2020: 应用活动量记录仪测量猴子的睡眠:与应用行为录像进行分析的比较. 动物学研究, 41(4): 437-443. DOI: 10.24272/j.issn.2095-8137.2020.056
引用本文: 秦冬冬, 冯书斐, 张飞宇, 王纳, 孙文杰, 周引, 熊腾芳, 徐仙来, 杨晓婷, 张祥, 朱雪, 胡新天, 熊磊, 刘芸, 陈永昌. 2020: 应用活动量记录仪测量猴子的睡眠:与应用行为录像进行分析的比较. 动物学研究, 41(4): 437-443. DOI: 10.24272/j.issn.2095-8137.2020.056
Dong-Dong Qin, Shu-Fei Feng, Fei-Yu Zhang, Na Wang, Wen-Jie Sun, Yin Zhou, Teng-Fang Xiong, Xian-Lai Xu, Xiao-Ting Yang, Xiang Zhang, Xue Zhu, Xin-Tian Hu, Lei Xiong, Yun Liu, Yong-Chang Chen. 2020: Potential use of actigraphy to measure sleep in monkeys: comparison with behavioral analysis from videography. Zoological Research, 41(4): 437-443. DOI: 10.24272/j.issn.2095-8137.2020.056
Citation: Dong-Dong Qin, Shu-Fei Feng, Fei-Yu Zhang, Na Wang, Wen-Jie Sun, Yin Zhou, Teng-Fang Xiong, Xian-Lai Xu, Xiao-Ting Yang, Xiang Zhang, Xue Zhu, Xin-Tian Hu, Lei Xiong, Yun Liu, Yong-Chang Chen. 2020: Potential use of actigraphy to measure sleep in monkeys: comparison with behavioral analysis from videography. Zoological Research, 41(4): 437-443. DOI: 10.24272/j.issn.2095-8137.2020.056

应用活动量记录仪测量猴子的睡眠:与应用行为录像进行分析的比较

Potential use of actigraphy to measure sleep in monkeys: comparison with behavioral analysis from videography

  • 摘要: 睡眠对于人类的健康必不可少,睡眠障碍会引发一系列负面后果。作为人类最近的亲属,应用非人类灵长类动物研究睡眠具有不可估量的价值,并且可以加深我们对人类睡眠和相关疾病的理解。以前在非人灵长类动物中测量睡眠主要是应用脑电图或行为录像技术。在该研究中,我们同时进行了行为录像和活动量记录,观察了10只食蟹猴7晚(每晚12小时)的睡眠模式。通过分析行为录像和活动量数据,应用相同的评分标准对动物的清醒、过渡睡眠和舒适睡眠的持续时间进行记录,并且比较两种睡眠分析方法。结果表明,活动量记录对于分析猴子的睡眠是可靠的,并且与行为录像分析得出的睡眠数据存在显著相关性。进一步分析表明,活动量记录更适合于评估舒适睡眠,与行为录像分析相比,活动量记录方法能正确识别出97.57%的舒适睡眠。只有34分钟(0.13%)和611分钟(2.30%)被错误地记录为清醒和过渡睡眠。该研究验证了睡眠分析的行为评分标准和活动量记录方法,可以成为应用脑电图和/或行为录像分析研究非人灵长类动物睡眠的有用和补充技术。

     

    Abstract: Sleep is indispensable for human health, with sleep disorders initiating a cascade of negative consequences. As our closest phylogenetic relatives, non-human primates (NHPs) are invaluable for comparative sleep studies and exhibit tremendous potential for improving our understanding of human sleep and related disorders. Previous work on measuring sleep in NHPs has mostly used electroencephalography or videography. In this study, simultaneous videography and actigraphy were applied to observe sleep patterns in 10 cynomolgus monkeys (Macaca fascicularis) over seven nights (12 h per night). The durations of wake, transitional sleep, and relaxed sleep were scored by analysis of animal behaviors from videography and actigraphy data, using the same behavioral criteria for each state, with findings then compared. Here, results indicated that actigraphy constituted a reliable approach for scoring the state of sleep in monkeys and showed a significant correlation with that scored by videography. Epoch-by-epoch analysis further indicated that actigraphy was more suitable for scoring the state of relaxed sleep, correctly identifying 97.57% of relaxed sleep in comparison with video analysis. Only 34 epochs (0.13%) and 611 epochs (2.30%) were differently interpreted as wake and transitional sleep compared with videography analysis. The present study validated the behavioral criteria and actigraphy methodology for scoring sleep, which can be considered as a useful and a complementary technique to electroencephalography and/or videography analysis for sleep studies in NHPs.

     

/

返回文章
返回